East Sussex Fire and Rescue Service were called at 22.53 to to reports of a fire at the waste site in Hollingdean Lane, Brighton.
Six fire engines are in attendance at the scene along with the Aerial Ladder Platform, support vehicles and officers.
As of 00:13 crews are using three jets, foam, three hydrants, breathing apparatus and the Ariel Ladder Platform to bring the blaze under control.
Due to the amount of smoke, please close all windows and doors.
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